Jesse Brock Pickering's Death

Jesse Brock Pickering, born on December 23, 1818, died on April 24, 1868. What I know about his death is that he was 49 years old. But Jesse came from a long line of long-lived men, his brothers were long-lived and his sons were long-lived. Here are the names and dates:

Fathers

• Father: Abel born 1792, lived to be 81 and he outlived Jesse,
• Grandfather: Jacob born 1756, lived to be 76,
• Great-grandfather: William born 1727, lived to be 69,
• Great-great-grandfather Samuel born 1684 lived to be 43, the only one younger than Jesse at his death.

Brothers

• Curtis Jordan born 1823 lived to be 80,
• Frank born 1835 lived to be 69,
• James born 1840 lived to be 64
• Jonathan W born 1843 death unknown

Sons

• Abel born 1837 lived to be 84,
• Joseph C. born 1839 lived to be 83,
• Isaac Orlando born 1842 lived to be 79,
• Vinson born 1850 lived to be 83,
• Charles S. born 1862 lived to be 75.

Yes, Jesse's death at 49 sticks out as an anomaly with the exception of his great-great-grandfather who lived 134 years earlier. 

Right now, I don't know much more than that. He was buried in the Quaker Cemetery - does that rule out suicide? He was a farmer - he could have suffered an unlucky accident. Perhaps it was illness. It does look like I can rule out hereditary illness.

One other thing I know. It destroyed the family. By the 1870 census, his widow was living with her newly married youngest daughter, his minor aged sons had been farmed out to family members and to non-family members. His older sons didn't take over the farm (perhaps he didn't own it) nor do they seem to have been able or interested in caring for their younger brothers. Jesse Brock didn't leave much in the way of material goods or prosperous family behind.